This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 956146.

Outreach

Elderly people illustrated

Publications

DOI:
Eksteen, G., Steenackers, N., Van der Schueren, B., Vanuytsel, T., and Matthy, C. (2022) ‘Selenium Deficiency After Bariatric Surgery Is More Than Surface Deep.’, Obesity Surgery, 32, pp. 32, 2473–2475.

DOI:
Stillhart, C., Asteriadis, A., Bocharova, E., Eksteen, G., Harder, F., Kusch, J., Tsakri, T., Augustijns, P., Matthys, C., Vertzoni, M., Weitschies, W., and Reppas, C. (2023) ‘The impact of advanced age on gastrointestinal characteristics that are relevant to oral drug absorption: An AGePOP review’, European Journal of Pharmaceutical Sciences, AGePOP VSI,  187.

DOI:
Hummler, H., Stillhart, C., Meilicke, L., Grimm, M., Krause, E., Mannaa, M., Gollasch, M., Weitschies, W., Page, S. (2023) ‘Impact of Tablet Size and Shape on the Swallowability in Older Adults’,  Pharmaceutics, 15, 1042.

DOI:
Hummler, H., Sarwinska, D., Weitschies, W., Gollasch, Maik, and Page, S. (2023) ‘Parameters to Consider for Successful Medication Use in Older Adults’, European Journal of Pharmaceutical Sciences, AGePOP VSI, 187.

DOI:
Hummler, H., Page, S., Stillhart, C., Meilicke, L., Grimm, M., Mannaa, M., Gollasch, M., Weitschies, W. (2023) ‘Influence of Solid Oral Dosage Form Characteristics on Swallowability, Visual Perception, and Handling in Older Adults’, Pharmaceutics, 15(4), p. 1315.

DOI:
Edwina, A., Dia, N., Dreesen, E., Vanassche, T., Verhamme, P., Spriet, I., Van der Linden, L., Tournoy, J. (2023) ‘Insights into the pharmacokinetics and pharmacodynamics of direct oral anticoagulants in older adults with atrial fibrillation: a structured narrative review’, Clinical Pharmacokinetics, 62, pp. 351-373.

DOI:
Demeester, C., Robins, D., Edwina, A., Tournoy, J., Augustijns, P., Ince, I., Lehmann, A., Vertzoni, M., and Schlender, J. (2023) ‘Physiologically Based Pharmacokinetic (PBPK) Modelling of Oral Drug Absorption in Older Adults’, European Journal of Pharmaceutical Sciences, 188.

DOI:
Tzakri, T., Rehenbrock, L., Senekowitsch, S., Rump, A., Schick, P., Krause, J., Kromrey, M.-L., Grimm, M., Weitschies, W. (2023) ‘Determination of Gastric Water Emptying in Fasted and Fed State Conditions Using a Compression-Coated Tablet and Salivary Caffeine Kinetics’, Pharmaceutics, 15, 2584.

Conference presentations

Hummler, H. (2023) ‘Acceptability of Solid Oral Dosage Forms in Older Adults’ [oral presentation], 6th APV Winterkonferenz. 19 January.

Hummler, H. (2023) ‘Impact of Size and Shape on the Preferences of Solid Oral Dosage Forms in Older Adults’ [type], 4th European Conference on Pharmaceutics. 20 March.

Sarwinska, D. (2022) ‘Real-life dosing conditions in geriatric patients’ [conference abstract], conference name. 4 November.

Tzakri, T., Rehenbrock, L., Senekowitsch, S., Rump, A., Schick, P., Krause, J., Grimm, M., and Weitschies, W. (2023) ‘Compression-coated tablet for the determination of gastric water emptying: development and in vivo validation’ [type], 4th European Conference on Pharmaceutics. 20 March.

Edwina, A., Dreesen, E., Hias, J., Koch, B., Van den Eede, N., Pauwels, S., Allegaert, K., Van der Linden, L., Spriet, I., and Tournoy, J. (2023) ‘Comparison of a colorimetric assay and ultra-performance liquid chromatography tandem mass spectrometry for quantifying paracetamol plasma concentrations: design of a geriatric pharmacokinetics study’ [poster], American Society of Clinical Pharmacology and Therapeutics. 22 March.

Harder, F. (2023) ‘The effect of sparkling water on the systemic pharmacokinetics of paracetamol in the elderly’ [oral presentation], 21st Forum of Pharmaceutical Sciences – Belgium Society of Pharmaceutical Sciences. 27 April.

Kusch, J. (2023) ‘Impact of aging on relative gene expression of tight junction proteins in duodenal and colonic epithelium: preliminary data’ [], AAPS PharmaSci 360. 22 October.

Hummler, H. (2023) ‘Acceptable Solid Oral Dosage Forms for Older Adults as Prerequisite for Medication Adherence – The Current Situation’ [], AAPS PharmaSci 360. 22 October.

Asteriadis, A. (2023) ‘Cognitive impairment on the physicochemical characteristics of fasting gastric contents of individuals in andavanced age: Initial data’ [], AAPS PharmaSci 360. 22 October.

Bocharova, E. (2023) ‘Clarifying the impact of advanced age on the physicochemical characteristics of gastric contents in the fasted state’ [], AAPS PharmaSci 360. 22 October.

Robins, D. (2023) ‘Expanding the Application of Global Sensitivity Analysis for Risk Assessment in Special Populations’ [], 14th American Conference on Pharmacometrics. 6 November.

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